Search on: CYCLIN-DEPENDENT KINASE 6 
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Descriptor English:   Cyclin-Dependent Kinase 6 
Descriptor Spanish:   Quinasa 6 Dependiente de la Ciclina 
Descriptor Portuguese:   Quinase 6 Dependente de Ciclina 
Synonyms English:   Cdk6 Protein Kinase  
Tree Number:   D08.811.913.696.620.682.700.200.515
D08.811.913.696.620.682.700.646.500.937
D12.644.360.250.515
D12.776.167.200.515
D12.776.476.250.515
Definition English:   Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during G1 PHASE of the CELL CYCLE. It helps regulate the transition to S PHASE and its kinase activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P18. 
History Note English:   2006(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50716 
Unique Identifier:   D051361 

Occurrence in VHL:
 

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